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Centre d'Immunologie et des Maladies Infectieuses
UPMC UMRS CR7 - Inserm U1135 - CNRS ERL 8255

Séminaire 20/12/17 - Stephan von Gunten (Univ. Bern)

13h, Salle 616 Bât "91"

Stephan von gunten (Inst. Pharmacology, Un. Bern, CH)

Title : TBA

 Invitant : G. Gorochov

Our laboratory is interested in molecular mechanisms that control inflammation and cancer. In particular, we focus on protein-carbohydrate interactions in the immune system and on anti-inflammatory effects mediated by Siglec receptors. Siglecs are carbohydrate-binding receptors (lectins) that have recently received particular attention in light of the capacity to mediate cell death, anti-proliferative effects, and inhibition of cellular activities. We recently identified natural autoantibodies within human intravenous immunoglobulin (IVIG) as endogenous Siglec receptor ligands. The group leader Dr. S. von Gunten is a participating investigator at the Consortium of Functional Glycomics (www.functionalglycomics.org), funded by the US National Institutes of Health (NIH), that aims at defining paradigms by which protein-carbohydrate interactions mediate cell communication. Our group has collaborations with scientists and clinicians from many international and local academic institutions, companies and hospitals.

09/11/17

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